Substance Encyclopedia

A potent serotonergic psychedelic known for its long duration, visual effects, and profound alterations of consciousness.

An empathogenic stimulant known for its prosocial effects, euphoria, and enhanced emotional openness.

A naturally occurring tryptamine psychedelic found in various mushroom species, known for introspective experiences.

A phenethylamine psychedelic with a unique combination of visual and tactile effects at moderate doses.

A dissociative anesthetic used medically and recreationally, known for dose-dependent dissociative and psychedelic effects.

A powerful short-acting tryptamine psychedelic known for intense visual experiences and reported entity encounters.

A widely used plant containing cannabinoids, primarily THC and CBD, producing relaxation and mild perceptual changes.

A powerful stimulant derived from the coca plant, producing intense but short-lived euphoria and energy.

A potent kappa-opioid agonist psychedelic known for its short but extremely intense dissociative-like effects.

An antihistamine that at high doses produces deliriant effects including realistic hallucinations. Carries significant health risks.

An over-the-counter cough suppressant that produces dose-dependent dissociative effects across four distinct "plateaus."

A class of depressant medications that enhance GABA activity, producing sedation, anxiety relief, and muscle relaxation.

Substances that bind to opioid receptors producing analgesia, euphoria, and sedation. High addiction and overdose potential.

A short-acting dissociative inhalant producing brief euphoria and mild dissociation. Risk of B12 depletion with chronic use.

An extremely potent tryptamine psychedelic found in the Bufo alvarius toad, known for ego-dissolution experiences.

A naturally occurring psychedelic alkaloid used in traditional Bwiti ceremonies and studied for addiction treatment.

A plant-based opioid-like substance with dose-dependent stimulant and sedative properties.

A naturally occurring phenethylamine psychedelic found in cacti, known for visual and introspective effects.