Psilocybin

Psychedelic

Magic Mushrooms • Shrooms • Caps • Psilocin • Boomers

Chemical class: Tryptamine

Overview

Psilocybin is a naturally occurring prodrug tryptamine psychedelic found in over 200 species of mushrooms. It is converted to psilocin in the body, which acts as a 5-HT2A receptor agonist. It is one of the most studied psychedelics for therapeutic applications.

Dosage

Oral (dried mushrooms)

Threshold

0.25 g

Light

0.5-1.5 g

Common

1.5-3.5 g

Strong

3.5-5 g

Heavy

5+ g

Oral (lemon tek)

Threshold

0.15 g

Light

0.3-1 g

Common

1-2.5 g

Strong

2.5-4 g

Heavy

4+ g

Dosage information is approximate. Individual sensitivity varies. Always start low and go slow.

Duration

Onset

20-45 minutes

Come-up

30-60 minutes

Peak

2-3 hours

Offset

1-2 hours

After Effects

2-6 hours

Total

4-7 hours

Visual Timeline

Onset
Come-up
Peak
Offset
After

Subjective Effects

Visual

  • Color enhancement
  • Pattern recognition
  • Geometry
  • Entity contact (high doses)
  • Symmetrical texture repetition

Cognitive

  • Introspection
  • Thought connectivity
  • Emotional breakthrough
  • Time distortion
  • Ego dissolution (high doses)

Physical

  • Body high
  • Nausea (come-up)
  • Pupil dilation
  • Yawning
  • Appetite suppression

Emotional

  • Euphoria
  • Emotional intensification
  • Empathy
  • Anxiety (possible)
  • Catharsis

Tolerance

Full Tolerance

Almost immediately after ingestion

Half Tolerance

5-7 days

Zero Tolerance

14 days

Cross-tolerance with:

LSDMescalineDMT

Interactions

Dangerous

LithiumTramadol

Unsafe

Cannabis (may increase anxiety)

Caution

SSRIs (may reduce effects)MAOIs (may potentiate)

Low Risk & Synergy

Benzodiazepines (trip killer)MDMA

Harm Reduction

  • 1

    Identify mushroom species carefully - misidentification can be fatal.

  • 2

    Start with a low dose, especially with a new batch or species.

  • 3

    Lemon tek may intensify and shorten the experience.

  • 4

    Have a trip sitter for doses above 3g.

  • 5

    Prepare ginger tea to help with come-up nausea.

  • 6

    Do not mix with lithium or tramadol.

  • 7

    Wait at least 2 weeks between experiences.

References